This happened again at work and thought I would post the “solution” for future reference.
Problem: After an installation/update of an Adobe product, the Windows 7 desktop loses connecting to off the network. After doing an ipconfig, there was an additional default gateway of 0.0.0.0 set so that the user can’t access any computer off their subnet. Settings the configurations from dhcp to static doesn’t solve the problem for very long.
The “solution” was find on this microsoft forum and basically boils down to running cmd with Administrative privs and running the following:
"C:\Program Files\Bonjour\mDNSResponder.exe" -remove